KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RB1
All Species:
18.18
Human Site:
S260
Identified Species:
33.33
UniProt:
P06400
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06400
NP_000312.2
928
106159
S260
P
R
R
G
Q
N
R
S
A
R
I
A
K
Q
L
Chimpanzee
Pan troglodytes
XP_509777
1075
122190
S407
P
R
R
G
Q
N
R
S
A
R
I
A
K
Q
L
Rhesus Macaque
Macaca mulatta
XP_001100383
928
106126
S260
P
R
R
G
Q
N
R
S
A
R
I
A
K
Q
L
Dog
Lupus familis
XP_534118
897
103170
Q235
R
S
A
R
I
A
K
Q
L
E
N
D
T
R
I
Cat
Felis silvestris
Mouse
Mus musculus
P13405
921
105320
S254
P
R
R
G
Q
N
R
S
A
R
I
A
K
Q
L
Rat
Rattus norvegicus
P33568
920
105007
S253
P
R
R
G
Q
N
R
S
A
R
I
A
K
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514098
917
104520
N245
R
T
S
R
R
G
Q
N
R
S
A
R
V
A
K
Chicken
Gallus gallus
Q90600
921
104417
N248
R
T
P
R
R
G
Q
N
R
N
A
R
A
S
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071248
903
102339
G246
R
T
S
R
R
N
Q
G
K
S
K
P
R
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395096
1006
113492
V244
P
Q
T
A
N
C
I
V
S
L
L
C
E
R
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790323
774
86478
I125
A
L
K
Q
K
Y
L
I
T
Y
A
I
F
C
K
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
E287
C
N
K
Y
D
T
S
E
E
V
L
R
K
S
M
Maize
Zea mays
Q3LXA7
1010
111475
E270
C
E
K
H
H
T
S
E
D
E
L
S
K
A
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
99.3
90
N.A.
90.4
89.7
N.A.
81.3
73
N.A.
53.9
N.A.
N.A.
23
N.A.
26.4
Protein Similarity:
100
86.3
99.5
93
N.A.
94.9
95.1
N.A.
88.2
84.1
N.A.
70.9
N.A.
N.A.
42.9
N.A.
42.6
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
0
N.A.
6.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
20
20
N.A.
26.6
N.A.
N.A.
40
N.A.
13.3
Percent
Protein Identity:
22.1
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
42.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
8
0
0
39
0
24
39
8
16
8
% A
% Cys:
16
0
0
0
0
8
0
0
0
0
0
8
0
8
0
% C
% Asp:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
16
8
16
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
39
0
16
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
8
0
8
8
0
0
39
8
0
0
8
% I
% Lys:
0
0
24
0
8
0
8
0
8
0
8
0
54
0
24
% K
% Leu:
0
8
0
0
0
0
8
0
8
8
24
0
0
0
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
8
47
0
16
0
8
8
0
0
0
0
% N
% Pro:
47
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% P
% Gln:
0
8
0
8
39
0
24
8
0
0
0
0
0
39
0
% Q
% Arg:
31
39
39
31
24
0
39
0
16
39
0
24
8
16
0
% R
% Ser:
0
8
16
0
0
0
16
39
8
16
0
8
0
16
0
% S
% Thr:
0
24
8
0
0
16
0
0
8
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _